LABORATORIOS HIPRA S.A. makes available interesting
questions that we belive may be usefull to you:
What are the differences between vaccines against myxomatosis? Homologous and heterologous vaccines differ in their antigenic composition. Although both have attenuated viruses, homologous vaccines are made with the myxomatosis virus, which is the same agent that causes the disease. Heterologous vaccines, on the contrary, contain Shope’s fibroma virus which is another poxvirus that has antigenic factors in common with myxomatosis virus and, therefore, confers cross protection against that disease. Homologous vaccines give protection for a much longer time than heterologous ones, but can produce more post-vaccinal reactions.
What kinds of vaccines are applied to protect breeding-rabbits against myxomatosis? The best results have been observed by administering a heterologous vaccine as the primo-vaccination, when one-month-old, and a homologous vaccine, 2 or 2.5 months later. Later semi-annual revaccinations with homologous vaccines protect does throughout their lifetime. The exclusive administration of heterologous vaccines is recommended when infection pressure is low, while if it is high, homologous vaccines may be used.
