What is the PRRS Virus?

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What is the PRRS Virus?



The PRRS virus belongs to the genus Arterivirus, the only genus in the family Arteriviridae, placed with the families Mesoniviridae, Roniviridae and Coronaviridae in the order Nidovirales.


    EAV: Equine arteritis virus
    WPDV: Wobbly possum disease virus
Genus Arterivirus   SHFV: Simian haemorrhagic fever virus
    LDV: Lactate dehydrogenase-elevating virus (mice)
    PRRSV: Porcine reproductive and respiratory syndrome virus 

All species in the genus Arterivirus have a nucleotide similarity of around 55-65%. Although arteriviruses share an evolutionary relationship with other members of the order, several of their characteristics are unique: genomic organisation; high genetic variability; morphology of the virion; limited cellular specificity (all replicate in alveolar macrophages, apart from WPDV, for which the cell type is yet unknown); and capacity to cause persistent or, in some cases, asymptomatic infections.

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