Combination of PRRS vaccine with PPV and SE vaccine in breeders improves piglet performance

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Combination of PRRS vaccine with PPV and SE vaccine in breeders improves piglet performance

Better performance has been demonstrated in piglets born to sows vaccinated with the combination of a live PRRS vaccine (UNISTRAIN® PRRS) with a PPV and SE vaccine (ERYSENG® PARVO) and challenged with a heterologous PRRSV strain.

In the swine industry, combining vaccines to minimise animal handling is a desirable practice. Nevertheless, vaccines may only be combined if their efficacy and safety in combination has been proven. It is absolutely necessary to obtain official authorisation and registration from the competent medical agencies in charge of evaluating the safety and efficacy of veterinary products. HIPRA is the first company in Europe to register the combination of a modified-live PRRS vaccine (UNISTRAIN® PRRS) and a PPV and SE vaccine (ERYSENG®PARVO). The efficacy of this new combination has been proven in PRRSvSE and PPV challenges.

Several studies have been performed to demonstrate the efficacy of the combined administration of UNISTRAIN®PRRS and ERYSENG® PARVO against porcine reproductive respiratory syndrome Virus (PRRSV). In the results presented below, the efficacy of the combined use of both vaccines was evaluated by assessing piglet performance during lactation after a heterologous PRRSV challenge.

To conduct the trial, clinically healthy six-month-old animals free from antibodies against PPV, E. rhusiopathiae and PRRS were selected and divided into vaccinated and control groups. The vaccinated group was immunised following the recommended protocol: vaccination seven weeks before mating with one dose of ERYSENG®PARVO (2 ml/dose) and revaccination four weeks before mating, i.e. three weeks later, with the combination of UNISTRAIN® PRRS and ERYSENG® PARVO (2 ml/dose). At ninety days of gestation, the vaccinated and control groups were challenged with a heterologous pathogenic PRRSV strain. After farrowing, all piglets were weighed at days 0 and 28 postpartum and observed during the lactation period.

Piglets born to sows in the control group were weaker than piglets born to vaccinated animals, and were also weaker and had less energy during the lactation period. Consequently, these piglets did not suck correctly and were more depressed, resulting in poor performance. The percentage of weaned piglets was significantly higher in the vaccinated group (93.81%) than in the control group (74.73%).

All piglets were weighed at birth, and those from the vaccinated group were heavier (1.36 kg) than those from the control group (1.22 kg). After 28 days in the farrowing units, piglets from vaccinated animals were heavier when weaned (6.64 kg) than piglets from animals in the control group (5.91 kg). Last but not least, average daily gain (g/piglet/day) was significantly higher in the vaccinated group versus the control group.

These results demonstrate that the combined use of UNISTRAIN® PRRS and ERYSENG® PARVO is an invaluable tool when it comes to protecting breeding herds faced with a heterologous PRRSV challenge. When assessing piglet performance, a huge improvement can be observed in those born to vaccinated breeders versus non-vaccinated breeders.