PRRS vaccination in suckling piglets: could it be interfered by maternal-derived antibodies?

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PRRS vaccination in suckling piglets: could it be interfered by maternal-derived antibodies?

Answered by: Young Lyoo I Published on: June 22, 2017



Question:
When suckling piglets are vaccinated with PRRS MLV, could it be interfered by maternal-derived antibodies? If so, should vaccination be delayed until weaning period or even later?


Answer:
Vaccination in suckling animals are always challenging because of maternally derived antibodies which interferes specific immune response in vaccinated animals.

PRRSV vaccine is not an exception and vaccination schedule needs to be adjusted based on the level of the colostrum antibody specific to PRRSV.

For piglets delivered from PRRSV vaccinated sows, vaccination schedule needs to be delayed after weaning. Evaluation of PRRSV specific antibody levels in piglets are essential to determine the proper vaccination schedule.

Since continuous sow vaccination elicit more uniform antibody levels than natural infection by the field strains, therefore it is much easier to adjust vaccination schedule.

 

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