Clostridium novyi toxin neutralization by sera from immunized sows with SUISENG®

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Clostridium novyi toxin neutralization by sera from immunized sows with SUISENG®

The objective of this study was to assess the serological response against α-toxin of C. novyi elicited by the immunization with Suiseng. This was accomplished using the sera of immunized sows of 4 independent studies. First of all, the IgG seroprofile was

About this article

Appeared in

IPVS Congress, 2012

Authors

Gibert, X.; Coronellas, J.; Ros, M.; Torrents, D.; Camprodon, A.

Summary

The results clearly demonstrate that SUISENG® induce the production of specific antibodies against the α-toxin of C. novyi. These antibodies last for at least 5 months, when a booster dose would be recommended. The neutralization assay demonstrates that the antibodies elicited by the immunization are biological active and they are able to neutralize completely the toxin. The sudden death attributable to the infection with C. novyi can be prevented by means of the neutralization of the main toxin responsible of the clinical signs. The immunization with SUISENG® induces the significant production neutralizing antibodies against α-toxin of C. novyi.

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