Immune response after an experimental intramammary challenge with killed Staphylococcus aureus in cows and heifers vaccinated and not vaccinated with STARTVAC®

Inicio Conocimiento Immune response after an experimental intramammary challenge with killed Staphylococcus aureus in cows and heifers vaccinated and not vaccinated with STARTVAC®

Immune response after an experimental intramammary challenge with killed Staphylococcus aureus in cows and heifers vaccinated and not vaccinated with STARTVAC®

An experimental trial was conducted to explore the effect of vaccination with a polyvalent vaccine against mastitis (STARTVAC®) on the early immune response after experimental intramammary challenge with a heterologous killed Staphylococcus aureus strain.

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Autores

Piepers, S.; Prenafeta, A.; Verbeke, J.; De Visscher, A.; March, R.; De Vliegher, S.

Resumen

Vaccinated cows had a less-severe inflammatory reaction after inoculation with a killed heterologous S. aureus strain compared with non-vaccinated animals. This possibly explains the absence of a substantial drop in milk production in the first days after challenge in the vaccinated animals compared with the nonvaccinated ones. The immune response against E. coli after vaccination was less pronounced than the immune response against S. aureus. Vaccination with STARTVAC® seems to evoke a strong Th2 response for S. aureus, characterized by a shift primarily toward the IgG1 antibody subtype

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