If antibodies against PRRSv are detected in a piglet under 48 hours of age by ELISA, does that mean that the piglet produced them at the end of gestation? or it is possible that they've been transferred from the sow via the placenta and/or colostrum?

Trang chủ Tri thức If antibodies against PRRSv are detected in a piglet under 48 hours of age by ELISA, does that mean that the piglet produced them at the end of gestation? or it is possible that they've been transferred from the sow via the placenta and/or colostrum?

If antibodies against PRRSv are detected in a piglet under 48 hours of age by ELISA, does that mean that the piglet produced them at the end of gestation? or it is possible that they've been transferred from the sow via the placenta and/or colostrum?

Answered by: Enric Mateu   I   Published on: April 21, 2016

Tight junctions in the gut of newborn piglets are loose enough for allowing absorption of immunoglobulins for the first 24-36 h after birth. The larger the volume of colostrum ingested, the higher the amount of IgG absorbed.

However, the larger the volume ingested, the faster junctions are closed. Therefore, blood taken from a piglet two days after birth is very likely to contain maternally-derived antibodies.

Regarding to transplacental transfer of antibodies, it is worth noting that pigs have an epitheliochorial placenta, namely, it is formed by six layers: maternal endothelial tissue, connective tissue and maternal endometrial tissue plus chorionic epithelial cells, foetal connective tissue and fetal endothelial tissue.

As a result, transfer of antibodies from sow to foetal pig is negligible.

 

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